Embryotoxicity of 4-deoxynivalenol (vomitoxin) in mice.
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چکیده
منابع مشابه
Murine Anorectic Response to Deoxynivalenol (Vomitoxin) Is Sex-Dependent
Deoxynivalenol (DON, vomitoxin), a common trichothecene mycotoxin found in cereal foods, dysregulates immune function and maintenance of energy balance. The purpose of this study was to determine if sex differences are similarly evident in DON's anorectic responses in mice. A bioassay for feed refusal, previously developed by our lab, was used to compare acute i.p. exposures of 1 and 5 mg/kg bw...
متن کاملDecline in deoxynivalenol (vomitoxin) concentrations in 1983 ontario winter wheat before harvest.
Samples of winter wheat were collected in 1983 from five fields in southwestern Ontario that were naturally infected with head blight. The geometric mean concentration of deoxynivalenol (vomitoxin) in the grain declined significantly from 1.56 mug/g on 7 July to 0.21 mug/g on 14 July and 0.11 mug/g on 18 July and did not increase at harvest (20 through 27 July).
متن کاملVomitoxin : Natural Occurrence on Cereal Grains and Significance as a Refusal and Emetic Factor to Swine
Fifty 12,13-epoxytrichothecenes have been reported in the literature; of these diacetoxyscirpenol, T-2 toxin, nivalenol and vomitoxin have been naturally occurring in cereal grains throughout the world. Vomitoxin is produced in ears of corn prior to harvest when wet, cool weather precedes which favours Gibberella zeae growth. This type of infected corn, which often contains vomitoxin, is associ...
متن کاملHigh Sensitivity of Aged Mice to Deoxynivalenol (Vomitoxin)-Induced Anorexia Corresponds to Elevated Proinflammatory Cytokine and Satiety Hormone Responses
Deoxynivalenol (DON), a trichothecene mycotoxin that commonly contaminates cereal grains, is a public health concern because of its adverse effects on the gastrointestinal and immune systems. The objective of this study was to compare effects of DON on anorectic responses in aged (22 mos) and adult (3 mos) mice. Aged mice showed increased feed refusal with both acute i.p. (1 mg/kg and 5 mg/kg) ...
متن کاملDiagnostic Vomitoxin ( Don ) Services in 1999 - 2000
Fusarium Head Blight (FHB) emerged in the 1990’s as an important problem for American agriculture. Resolving the FHB problem involves cooperative efforts and a multidisciplinary approach, including analytical assays for vomitoxin in the new wheat and barley varieties. In 1999, the US Wheat and Barley Scab Initiative provided grants, for diagnostic vomitoxin (DON) services, to 4 laboratories in ...
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ورودعنوان ژورنال:
- Bulletin of environmental contamination and toxicology
دوره 29 4 شماره
صفحات -
تاریخ انتشار 1982